You know you’re too fucking science geeky when you insult someone by saying, “do you have trisomy 18 or something?”. The closest you get to anyone knowing what you might be talking about is the (very) few people who say, “Down Syndrome??”. Then you have to say, “No, that’s trisomy 21, this is Edwards syndrome, it’s worse.”
So I’m back to calling people fatuous, at least I can send them to dictionary.com to look it up if they don’t know it (though, really, it’s more fitting when they don’t)